Enhanced neuroinflammation and pain hypersensitivity after peripheral nerve injury in rats expressing mutated superoxide dismutase 1

BACKGROUND: Neuroinflammation and nitroxidative stress are implicated in the pathophysiology of neuropathic pain. In view of both processes, microglial and astroglial activation in the spinal dorsal horn play a predominant role. The present study investigated the severity of neuropathic pain and the...

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Bibliografiske detaljer
Main Authors: Berger, Julie V, Deumens, Ronald, Goursaud, Stéphanie, Schäfer, Sabrina, Lavand'homme, Patricia, Joosten, Elbert A, Hermans, Emmanuel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090736/
https://ncbi.nlm.nih.gov/pubmed/21489258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-33
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