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Mechanism of dioxin action: receptor-enhancer interactions in intact cells.
We have used a ligation-mediated polymerase chain reaction technique to analyze protein-DNA interactions at a dioxin-responsive enhancer upstream of the CYP1A1 gene in intact mouse hepatoma cells. In its inactive state, the enhancer binds few, if any, proteins within the major DNA groove in vivo. Th...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1993
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| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8382788/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.1.119 |
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