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Sequences at the C-terminus of the herpes simplex virus type 1 UL30 protein are dispensable for DNA polymerase activity but not for viral origin-dependent DNA replication.

The UL30 protein of herpes simplex virus type 1 (HSV-1) is a catalytically active DNA polymerase which is present in virus infected cells in a heterodimeric complex with an accessory subunit, the UL42 polypeptide. Both proteins are essential for viral DNA synthesis but because the UL42 protein is mu...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Autor principal: Stow, N D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1993
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8382792/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.1.87
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