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Telomere directed fragmentation of mammalian chromosomes.

Cloned human telomeric DNA can integrate into mammalian chromosomes and seed the formation of new telomeres. This process occurs efficiently in three established human cell lines and in a mouse embryonic stem cell line. The newly seeded telomeres appear to be healed by telomerase. The seeding of new...

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Detalhes bibliográficos
Main Authors: Barnett, M A, Buckle, V J, Evans, E P, Porter, A C, Rout, D, Smith, A G, Brown, W R
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC309061/
https://ncbi.nlm.nih.gov/pubmed/8441617
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