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NEMO kinase contributes to core period determination by slowing the pace of the Drosophila circadian oscillator

The Drosophila circadian oscillator is comprised of transcriptional feedback loops that are activated by CLOCK (CLK) and CYCLE (CYC) and repressed by PERIOD (PER) and TIMELESS (TIM) [1]. The timing of CLK-CYC activation and PER-TIM repression is regulated post-translationally, in part through rhythm...

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Detalhes bibliográficos
Main Authors: Yu, Wangjie, Houl, Jerry H., Hardin, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090582/
https://ncbi.nlm.nih.gov/pubmed/21514156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.02.037
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