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NEMO kinase contributes to core period determination by slowing the pace of the Drosophila circadian oscillator

The Drosophila circadian oscillator is comprised of transcriptional feedback loops that are activated by CLOCK (CLK) and CYCLE (CYC) and repressed by PERIOD (PER) and TIMELESS (TIM) [1]. The timing of CLK-CYC activation and PER-TIM repression is regulated post-translationally, in part through rhythm...

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Autori principali: Yu, Wangjie, Houl, Jerry H., Hardin, Paul E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090582/
https://ncbi.nlm.nih.gov/pubmed/21514156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.02.037
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