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Differential response related to genotoxicity in multiple organs of cirrhotic rats

PURPOSE: The aim of this study was to use the single cell gel (comet) assay to investigate whether blood, liver, heart, kidney, and brain are particularly sensitive organs for DNA damage in cirrhotic rats to predict genetic instability induced by cirrhosis. METHODS: A total of 16 male Wistar rats (n...

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Detalhes bibliográficos
Main Authors: Nagaoka, Marcia R., Le Sueur-Maluf, Luciana, Aguiar, Odair, Castro, Glaucia M., Spadari-Bratfisch, Regina C., Ribeiro, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090554/
https://ncbi.nlm.nih.gov/pubmed/21484143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-010-9239-6
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