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Type 1 Equilibrative Nucleoside Transporter Regulates Ethanol Drinking through Accumbal N-Methyl-D-Aspartate Receptor Signaling

BACKGROUND: Mice lacking type 1 equilibrative nucleoside transporter (ENT1(−/−)) exhibit increased ethanol-preferring behavior compared to wild-type littermates. This phenotype of ENT1(−/−) mice appears to be correlated with increased glutamate levels in the nucleus accumbens (NAc). However, little...

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Bibliographic Details
Main Authors: Nam, Hyung Wook, Lee, Moonnoh R., Zhu, Yu, Wu, Jinhua, Hinton, David J., Choi, Sun, Kim, Taehyun, Hammack, Nora, Yin, Jerry C.P., Choi, Doo-Sup
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090461/
https://ncbi.nlm.nih.gov/pubmed/21489406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.02.013
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