An NFKB1 Promoter Insertion/Deletion Polymorphism Influences Risk and Outcome in Acute Respiratory Distress Syndrome among Caucasians

BACKGROUND: Nuclear factor-κB (NF-κB) is required for transcription of many pro-inflammatory genes and has been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS). We hypothesized that a known functional polymorphism in the promoter of the NFKB1 gene may affect susceptibili...

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Autors principals: Bajwa, Ednan K., Cremer, Paul C., Gong, Michelle N., Zhai, Rihong, Su, Li, Thompson, B. Taylor, Christiani, David C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090449/
https://ncbi.nlm.nih.gov/pubmed/21573030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019469
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