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Induction of TLR-2 and TLR-5 Expression by Helicobacter pylori Switches cagPAI-Dependent Signalling Leading to the Secretion of IL-8 and TNF-α
Helicobacter pylori is the causative agent for developing gastritis, gastric ulcer, and even gastric cancer. Virulent strains carry the cag pathogenicity island (cagPAI) encoding a type-IV secretion system (T4SS) for injecting the CagA protein. However, mechanisms of sensing this pathogen through To...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090411/ https://ncbi.nlm.nih.gov/pubmed/21573018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019614 |
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