Induction of TLR-2 and TLR-5 Expression by Helicobacter pylori Switches cagPAI-Dependent Signalling Leading to the Secretion of IL-8 and TNF-α

Helicobacter pylori is the causative agent for developing gastritis, gastric ulcer, and even gastric cancer. Virulent strains carry the cag pathogenicity island (cagPAI) encoding a type-IV secretion system (T4SS) for injecting the CagA protein. However, mechanisms of sensing this pathogen through To...

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Main Authors: Kumar Pachathundikandi, Suneesh, Brandt, Sabine, Madassery, Joseph, Backert, Steffen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090411/
https://ncbi.nlm.nih.gov/pubmed/21573018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019614
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