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HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic intervention

The HIV protein, Vpr, is a multifunctional accessory protein critical for efficient viral infection of target CD4(+ )T cells and macrophages. Vpr is incorporated into virions and functions to transport the preintegration complex into the nucleus where the process of viral integration into the host g...

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Detalhes bibliográficos
Main Authors: Kogan, Michael, Rappaport, Jay
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090340/
https://ncbi.nlm.nih.gov/pubmed/21489275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-25
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