Chargement en cours...
The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9
Mutations in the ATRX protein are associated with the alpha-thalassemia and mental retardation X-linked syndrome (ATR-X). Almost half of the disease-causing mutations occur in its ATRX-Dnmt3-Dnmt3L (ADD) domain. By employing peptide arrays, chromatin pull-down and peptide binding assays, we show spe...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2011
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090196/ https://ncbi.nlm.nih.gov/pubmed/21421568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr107 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|