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Txe, an endoribonuclease of the enterococcal Axe–Txe toxin–antitoxin system, cleaves mRNA and inhibits protein synthesis

The axe–txe operon encodes a toxin–antitoxin (TA) pair, Axe–Txe, that was initially identified on the multidrug-resistance plasmid pRUM in Enterococcus faecium. In Escherichia coli, expression of the Txe toxin is known to inhibit cell growth, and co-expression of the antitoxin, Axe, counteracts the...

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Autors principals: Halvorsen, Elizabeth M., Williams, Julia J., Bhimani, Azra J., Billings, Emily A., Hergenrother, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: Microbiology Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090131/
https://ncbi.nlm.nih.gov/pubmed/21030436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.045492-0
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