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Neuroinflammation Leads to Region-Dependent Alterations in Astrocyte Gap Junction Communication and Hemichannel Activity

Inflammation attenuates gap junction (GJ) communication in cultured astrocytes. Here we used a well-characterized model of experimental brain abscess as a tool to query effects of the CNS inflammatory milieu on astrocyte GJ communication and electrophysiological properties. Whole-cell patch-clamp re...

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Detalles Bibliográficos
Main Authors: Karpuk, Nikolay, Burkovetskaya, Maria, Fritz, Teresa, Angle, Amanda, Kielian, Tammy
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089986/
https://ncbi.nlm.nih.gov/pubmed/21228152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5247-10.2011
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