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Nerve-derived Sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells

In adult skin, stem cells in the hair follicle bulge cyclically regenerate the follicle, whereas a distinct stem cell population maintains the epidermis. The degree to which all bulge cells have equal regenerative potential is not known. We found that Sonic hedgehog (Shh) from neurons signals to a n...

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Hlavní autoři: Brownell, Isaac, Guevara, Elizabeth, Bai, C. Brian, Loomis, Cynthia A., Joyner, Alexandra L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089905/
https://ncbi.nlm.nih.gov/pubmed/21549329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.02.021
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