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Caudal Granular Insular Cortex Is Sufficient and Necessary for the Long-Term Maintenance of Allodynic Behavior in the Rat Attributable to Mononeuropathy

Mechanical allodynia, the perception of innocuous tactile stimulation as painful, is a severe symptom of chronic pain often produced by damage to peripheral nerves. Allodynia affects millions of people and remains highly resistant to classic analgesics and therapies. Neural mechanisms for the develo...

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Autores principales: Benison, Alexander M., Chumachenko, Serhiy, Harrison, Jacqueline A., Maier, Steven F., Falci, Scott P., Watkins, Linda R., Barth, Daniel S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089761/
https://ncbi.nlm.nih.gov/pubmed/21525272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0076-11.2011
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