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Inhibition of the AMP-activated Protein Kinase Alpha 2 Accentuates Agonist-Induced Vascular Smooth Muscle Contraction and High Blood Pressure in Mice
The aim of the present study was to determine the effects and molecular mechanisms by which AMP-activated protein kinase (AMPK) regulates smooth muscle contraction and blood pressure in mice. In cultured human vascular smooth muscle cells (HMSC), we observed that activation of AMPK by AICAR (5-amino...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3089757/ https://ncbi.nlm.nih.gov/pubmed/21464390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.168906 |
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