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Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C

A recently recognized human rhinovirus species C (HRV-C) is associated with up to half of HRV infections in young children. Here we propagated two HRV-C isolates ex vivo in organ culture of nasal epithelial cells, sequenced a new C15 isolate and developed the first, to our knowledge, reverse genetic...

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Autores principales: Bochkov, Yury A, Palmenberg, Ann C, Lee, Wai-Ming, Rathe, Jennifer A, Amineva, Svetlana P, Sun, Xin, Pasic, Thomas R, Jarjour, Nizar N, Liggett, Stephen B, Gern, James E
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group US 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089712/
https://ncbi.nlm.nih.gov/pubmed/21483405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2358
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