Non-Truncated Amino-Terminal PTH Overproduction in Two Patients with Parathyroid Carcinoma: A Possible Link to HRPT2 Gene Inactivation

OBJECTIVE: Some patients with parathyroid carcinoma present with an over-production of non-truncated amino-terminal (NT-N) PTH, a post-transcriptionally modified form of PTH(1-84). This is usually picked up on an elevated Whole (W) PTH (3(rd) generation) / Total (T) (2(nd) generation) PTH assay rati...

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Détails bibliographiques
Auteurs principaux: Caron, Philippe, Simonds, William F., Maiza, Jean-Christophe, Rubin, Mishaela, Cantor, Tom, Rousseau, Louise, Bilezikian, John P., Souberbielle, Jean-Claude, D'Amour, Pierre
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089698/
https://ncbi.nlm.nih.gov/pubmed/21521290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2265.2011.04021.x
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