THE FOK1 VITAMIN D RECEPTOR GENE POLYMORPHISM IS ASSOCIATED WITH PLASMA RENIN ACTIVITY IN CAUCASIANS

OBJECTIVES: 25-hydroxyvitamin D (25[OH]D) deficiency and excess activity of the renin-angiotensin system (RAS) are both associated with cardiovascular disease. Vitamin D interacts with the vitamin D receptor (VDR) to negatively regulate renin expression in mice; however, human studies linking geneti...

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Detalhes bibliográficos
Main Authors: Vaidya, Anand, Sun, Bei, Forman, John P., Hopkins, Paul N., Brown, Nancy J., Kolatkar, Nikheel S., Williams, Gordon H., Williams, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089671/
https://ncbi.nlm.nih.gov/pubmed/21521263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2265.2011.03991.x
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