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Modification of Collagen by 3-Deoxyglucosone Alters Wound Healing through Differential Regulation of p38 MAP Kinase

BACKGROUND: Wound healing is a highly dynamic process that requires signaling from the extracellular matrix to the fibroblasts for migration and proliferation, and closure of the wound. This rate of wound closure is impaired in diabetes, which may be due to the increased levels of the precursor for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Loughlin, Danielle T., Artlett, Carol M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089600/
https://ncbi.nlm.nih.gov/pubmed/21573155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018676
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