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Phosphorylation of Connexin 50 by Protein Kinase A Enhances Gap Junction and Hemichannel Function

Phosphorylation of connexins is an important mechanism regulating gap junction channels. However, the role(s) of connexin (Cx) phosphorylation in vivo are largely unknown. Here, we showed by mass spectrometry that Ser-395 in the C terminus of chicken Cx50 was phosphorylated in the lens. Ser-395 is l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Jialu, Ek Vitorin, Jose F., Weintraub, Susan T., Gu, Sumin, Shi, Qian, Burt, Janis M., Jiang, Jean X.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089535/
https://ncbi.nlm.nih.gov/pubmed/21454606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.218735
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