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USP10 deubiquitylates the histone variant H2A.Z and both are required for androgen receptor-mediated gene activation

H2A.Z, a variant of H2A, is found at the promoters of inducible genes in both yeast and higher eukaryotes. However, its role in transcriptional regulation is complex since it has been reported to function both as a repressor and activator. We have previously found that mono-ubiquitylation of H2A.Z i...

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Autors principals: Draker, Ryan, Sarcinella, Elizabeth, Cheung, Peter
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089478/
https://ncbi.nlm.nih.gov/pubmed/21245042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1352
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