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An Enzymatically Active A Domain Is Required for Cholera-Like Enterotoxins To Induce a Long-Lived Blockade on the Induction of Oral Tolerance: New Method for Screening Mucosal Adjuvants

The cholera-like enterotoxins (CLETS), cholera toxin (CT) and Escherichia coli heat-labile toxin (LT), are powerful mucosal adjuvants. Here we show that these toxins also induce a long-lived blockade (of at least 6 months) on the induction of oral tolerance when they are coadministered with the anti...

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Detalles Bibliográficos
Autores principales: Bagley, Kenneth C., Abdelwahab, Sayed F., Tuskan, Robert G., Lewis, George K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC308947/
https://ncbi.nlm.nih.gov/pubmed/14638772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.6850-6856.2003
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