Inducible Nitric Oxide Synthase Regulates Production of Isoprostanes In Vivo during Chlamydial Genital Infection in Mice

Urinary nitrite and F(2)-isoprostanes, an index of oxidant stress, were elevated during chlamydial genital infection of mice. Enhancement of urinary nitrite and F(2)-isoprostanes was observed in phagocyte oxidase-deficient mice. Inhibition of inducible nitric oxide synthase reduced isoprostane excre...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Ramsey, K. H., Sigar, I. M., Rana, S. V., Gupta, J., Holland, S. M., Byrne, G. I., Morrow, J. D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2003
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638813/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.12.7183-7187.2003
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