CD8(+)-T-Cell Responses of Mycobacterium-Infected Mice to a Newly Identified Major Histocompatibility Complex Class I-Restricted Epitope Shared by Proteins of the ESAT-6 Family

Here we describe the identification of a new CD8(+)-T-cell epitope, the GYAGTLQSL nonamer, shared by the TB10.3 and TB10.4 proteins of the Mycobacterium tuberculosis ESAT-6 family. Cytotoxic T cells from mycobacterium-infected mice efficiently recognized this epitope. GYAGTLQSL-specific T-cell hybri...

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Hlavní autoři: Majlessi, Laleh, Rojas, Marie-Jésus, Brodin, Priscille, Leclerc, Claude
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC308897/
https://ncbi.nlm.nih.gov/pubmed/14638811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7173-7177.2003
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