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High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels

Channelrhodopsin-2 (ChR2) has become an indispensable tool in neuroscience, allowing precise induction of action potentials with short light pulses. A limiting factor for many optophysiological experiments is the relatively small photocurrent induced by ChR2. We screened a large number of ChR2 point...

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Detalhes bibliográficos
Main Authors: Berndt, André, Schoenenberger, Philipp, Mattis, Joanna, Tye, Kay M., Deisseroth, Karl, Hegemann, Peter, Oertner, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088623/
https://ncbi.nlm.nih.gov/pubmed/21504945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017210108
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