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Replication of the TCF4 Intronic Variant in Late-Onset Fuchs Corneal Dystrophy and Evidence of Independence from the FCD2 Locus

PURPOSE. Fuchs corneal dystrophy (FCD) is an autosomal dominant disease of the corneal endothelium with variable penetrance and expressivity. Recently, rs613872, an intronic variation of TCF4 associated with late-onset FCD, was reported. The present study was undertaken to examine this association i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Riazuddin, S. Amer, McGlumphy, Elyse J., Yeo, William S., Wang, Jiangxia, Katsanis, Nicholas, Gottsch, John D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association for Research in Vision and Ophthalmology, Inc. 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088564/
https://ncbi.nlm.nih.gov/pubmed/21245398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6497
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