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Control of Exocytosis by Synaptotagmins and Otoferlin in Auditory Hair Cells

In pre-hearing mice, vesicle exocytosis at cochlear inner hair cell (IHC) ribbon synapses is triggered by spontaneous Ca(2+) spikes. At the onset of hearing, IHC exocytosis is then exclusively driven by graded potentials, and is characterized by higher Ca(2+) efficiency and improved synchronization...

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Détails bibliographiques
Auteurs principaux: Beurg, Maryline, Michalski, Nicolas, Safieddine, Saaid, Bouleau, Yohan, Schneggenburger, Ralf, Chapman, Edwin R., Petit, Christine, Dulon, Didier
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088501/
https://ncbi.nlm.nih.gov/pubmed/20926654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2528-10.2010
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