Prevention of peptic ulcers with esomeprazole in patients at risk of ulcer development treated with low-dose acetylsalicylic acid: a randomised, controlled trial (OBERON)

OBJECTIVE: To determine whether once-daily esomeprazole 40 mg or 20 mg compared with placebo reduces the incidence of peptic ulcers over 26 weeks of treatment in patients taking low-dose acetylsalicylic acid (ASA) and who are at risk for ulcer development. DESIGN: Multinational, randomised, blinded,...

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Main Authors: Scheiman, James M, Devereaux, P J, Herlitz, Johan, Katelaris, Peter H, Lanas, Angel, Veldhuyzen van Zanten, Sander, Nauclér, Emma, Svedberg, Lars-Erik
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2011
Fag:
Clinical Trials
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088470/
https://ncbi.nlm.nih.gov/pubmed/21415072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2010.217547
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