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An empirical assessment of validation practices for molecular classifiers
Proposed molecular classifiers may be overfit to idiosyncrasies of noisy genomic and proteomic data. Cross-validation methods are often used to obtain estimates of classification accuracy, but both simulations and case studies suggest that, when inappropriate methods are used, bias may ensue. Bias c...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088312/ https://ncbi.nlm.nih.gov/pubmed/21300697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbq073 |
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