Selection of Clinically Relevant Protease Inhibitor-Resistant Viruses Using the Genotype 2a Hepatitis C Virus Infection System

Treatment of patients infected with hepatitis C virus (HCV) with direct acting antivirals can lead to the emergence of drug-resistant variants that may pose a long-term threat to viral eradication. HCV replicons have been used to select resistance mutations; however, genotype 2a JFH-1-based viruses...

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Bibliografiske detaljer
Main Authors: Cheng, Guofeng, Chan, Katie, Yang, Huiling, Corsa, Amy, Pokrovskii, Maria, Paulson, Matthew, Bahador, Gina, Zhong, Weidong, Delaney, William
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088261/
https://ncbi.nlm.nih.gov/pubmed/21357305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01382-10
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