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Aspergillus fumigatus Strains with Mutations in the cyp51A Gene Do Not Always Show Phenotypic Resistance to Itraconazole, Voriconazole, or Posaconazole

We performed molecular identification of 98 Aspergillus fumigatus complex isolates with MICs of 1 to 4 μg/ml for itraconazole and searched for the presence of mutations in cyp51A. Most of the isolates (91%) belonged to A. fumigatus sensu stricto. We found 14 different mutations in nine isolates at c...

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Hlavní autoři: Escribano, Pilar, Recio, Sandra, Peláez, Teresa, Bouza, Emilio, Guinea, Jesús
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088257/
https://ncbi.nlm.nih.gov/pubmed/21321141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01358-10
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