Loss of Mitochondrial Functions Associated with Azole Resistance in Candida glabrata Results in Enhanced Virulence in Mice

Mitochondrial dysfunction is one of the possible mechanisms by which azole resistance can occur in Candida glabrata. Cells with mitochondrial DNA deficiency (so-called “petite mutants”) upregulate ATP binding cassette (ABC) transporter genes and thus display increased resistance to azoles. Isolation...

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Hlavní autoři: Ferrari, Sélène, Sanguinetti, Maurizio, De Bernardis, Flavia, Torelli, Riccardo, Posteraro, Brunella, Vandeputte, Patrick, Sanglard, Dominique
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088236/
https://ncbi.nlm.nih.gov/pubmed/21321146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01271-10
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