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Evaluation of Mitochondrial Toxicity in Marmota himalayana Treated with Metacavir, a Novel 2′,3′-Dideoxyguanosine Prodrug for Treatment of Hepatitis B Virus
Metacavir (PNA) is a novel synthetic nucleoside analogue for the treatment of hepatitis B virus (HBV). Our recent studies showed that PNA, a prodrug of 2′,3′-dideoxyguanosine (ddG), exhibited lower mitochondrial toxicity in long-term cultures of HepG2 cells. In the current study, we examined the lon...
Tallennettuna:
| Päätekijät: | , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088222/ https://ncbi.nlm.nih.gov/pubmed/21282436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01520-10 |
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