Population Pharmacokinetic and Pharmacodynamic Analysis of Linezolid and a Hematologic Side Effect, Thrombocytopenia, in Japanese Patients

Linezolid is an antimicrobial agent to treat infections by Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). While effective, linezolid treatment frequently is associated with hematological side effects, especially thrombocytopenia. However, little is known about...

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Detalhes bibliográficos
Main Authors: Sasaki, Tomohiro, Takane, Hiroshi, Ogawa, Katsuhiro, Isagawa, Sayaka, Hirota, Takeshi, Higuchi, Shun, Horii, Toshinobu, Otsubo, Kenji, Ieiri, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088209/
https://ncbi.nlm.nih.gov/pubmed/21357301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01185-10
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