Emergence of Linezolid-Resistant Mutants in a Susceptible-Cell Population of Methicillin-Resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus with a MIC of linezolid of 4 μg/ml, isolated from a patient who had undergone unsuccessful linezolid therapy, yielded linezolid-resistant mutants in blood agar at 48 h of incubation. The resistant clones showed a MIC of linezolid ranging from 8 to 64 μg/ml...

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Main Authors: Ikeda-Dantsuji, Yurika, Hanaki, Hideaki, Nakae, Taiji, Takesue, Yoshio, Tomono, Kazunori, Honda, Junichi, Yanagihara, Katsunori, Mikamo, Hiroshige, Fukuchi, Kunihiko, Kaku, Mitsuo, Kohno, Shigeru, Niki, Yoshihito
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Mechanisms of Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088184/
https://ncbi.nlm.nih.gov/pubmed/21357291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01548-10
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