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Analysis of Murine Genetic Predisposition to Pneumococcal Infection Reveals a Critical Role of Alveolar Macrophages in Maintaining the Sterility of the Lower Respiratory Tract

The study of pathogenic mechanisms of disease can be greatly facilitated by studying genetic differences in susceptibility to infection. In the present study, we compared the severity of pneumococcal infection in C57BL/6 (B6) and 129Sv mice. The results showed that 129Sv mice were remarkably more su...

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Detalhes bibliográficos
Main Authors: Sun, Keer, Gan, Yan, Metzger, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088159/
https://ncbi.nlm.nih.gov/pubmed/21321074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01143-10
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