Legionella pneumophila Type II Secretion Dampens the Cytokine Response of Infected Macrophages and Epithelia

The type II secretion (T2S) system of Legionella pneumophila is required for the ability of the bacterium to grow within the lungs of A/J mice. By utilizing mutants lacking T2S (lsp), we now document that T2S promotes the intracellular infection of both multiple types of macrophages and lung epithel...

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Detalhes bibliográficos
Main Authors: McCoy-Simandle, Kessler, Stewart, Catherine R., Dao, Jenny, DebRoy, Sruti, Rossier, Ombeline, Bryce, Paul J., Cianciotto, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088156/
https://ncbi.nlm.nih.gov/pubmed/21383054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01077-10
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