Antigen-Specific CD8(+) T Cells Fail To Respond to Shigella flexneri

CD8(+) T lymphocytes often play a primary role in adaptive immunity to cytosolic microbial pathogens. Surprisingly, CD8(+) T cells are not required for protective immunity to the enteric pathogen Shigella flexneri, despite the ability of Shigella to actively secrete proteins into the host cytoplasm,...

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Detalhes bibliográficos
Main Authors: Jehl, Stephanie P., Doling, Amy M., Giddings, Kara S., Phalipon, Armelle, Sansonetti, Philippe J., Goldberg, Marcia B., Starnbach, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088127/
https://ncbi.nlm.nih.gov/pubmed/21357720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00939-10
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