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Antigen-Specific CD8(+) T Cells Fail To Respond to Shigella flexneri

CD8(+) T lymphocytes often play a primary role in adaptive immunity to cytosolic microbial pathogens. Surprisingly, CD8(+) T cells are not required for protective immunity to the enteric pathogen Shigella flexneri, despite the ability of Shigella to actively secrete proteins into the host cytoplasm,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jehl, Stephanie P., Doling, Amy M., Giddings, Kara S., Phalipon, Armelle, Sansonetti, Philippe J., Goldberg, Marcia B., Starnbach, Michael N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088127/
https://ncbi.nlm.nih.gov/pubmed/21357720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00939-10
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