Death Associated Protein Kinase 1 Phosphorylates Pin1 and Inhibits its Prolyl Isomerase Activity and Cellular Function

Pin1 is a phospho-specific prolyl isomerase that regulates numerous key signaling molecules and whose deregulation contributes to disease notably cancer. However, since prolyl isomerases are often believed to be constitutively active, little is known whether and how Pin1 catalytic activity is regula...

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Bibliografiske detaljer
Main Authors: Lee, Tae Ho, Chen, Chun-Hau, Suizu, Futoshi, Huang, Pengyu, Schiene-Fischer, Cordelia, Daum, Sebastian, Zhang, Yan Jessie, Goate, Alison, Chen, Ruey-Hwa, Zhou, Xiao Zhen, Lu, Kun Ping
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088080/
https://ncbi.nlm.nih.gov/pubmed/21497122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.005
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