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Bortezomib treatment causes remission in a Ph+ALL patient and reveals FoxO as a theranostic marker

BCR-ABL is a key mediator in the pathogenesis of all cases of chronic myelogenous leukemia (CML) and a subset of precursor B-acute lymphoblastic leukemia (Ph+ALL). Previous animal and cell-based studies have shown that the expression of members of the Forkhead family of tumor suppressors, including...

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Detalhes bibliográficos
Main Authors: Dewar, Rajan, Chen, Sing-Tsung, Yeckes-Rodin, Heather, Miller, Kenneth, Khosravi-Far, Roya
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087959/
https://ncbi.nlm.nih.gov/pubmed/21282974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.6.14675
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