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The death-promoting molecule tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is not required for the development of peripheral lymphopenia or granuloma necrosis during infection with virulent Mycobacterium avium

Disseminated infection with virulent Mycobacterium avium in C57Bl/6 (B6) mice leads to severe lymphocyte depletion in secondary lymphoid organs. In this study, we found an up-regulation of caspase-8 activity in spleen cell extracts from M. avium 25291-infected B6 mice compared to non-infected mice....

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Autors principals: Borges, M, Rosa, G T, Appelberg, R
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087937/
https://ncbi.nlm.nih.gov/pubmed/21470210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04385.x
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