Importance of B cell co-stimulation in CD4(+) T cell differentiation: X-linked agammaglobulinaemia, a human model

We were interested in the question of whether the congenital lack of B cells actually had any influence on the development of the T cell compartment in patients with agammaglobulinaemia. Sixteen patients with X-linked agammaglobulinaemia (XLA) due to mutations in Btk, nine patients affected by commo...

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Dettagli Bibliografici
Autori principali: Martini, H, Enright, V, Perro, M, Workman, S, Birmelin, J, Giorda, E, Quinti, I, Lougaris, V, Baronio, M, Warnatz, K, Grimbacher, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2011
Soggetti:
Translational Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087934/
https://ncbi.nlm.nih.gov/pubmed/21488866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04377.x
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