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Plasmodium-host interactions directly influence the threshold of memory CD8 T cells required for protective immunity
Plasmodium infections are responsible for millions of cases of malaria and about one million deaths annually. Recently, we showed that sterile protection (95%) in BALB/c mice required P. berghei circumsporozoite (CS(252-260))-specific memory CD8 T-cells exceeding a threshold of ≥1% of all PBL. Impor...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3087867/ https://ncbi.nlm.nih.gov/pubmed/21460205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100194 |
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