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Structure of the uncomplexed Neisseria meningitidis factor H-binding protein fHbp (rLP2086)

fHbp, a highly immunogenic outer membrane protein of Neisseria meningitidis, is responsible for binding to human factor H, a multi-domain protein which is the central regulator of the alternative complement pathway. Here, the crystal structure of mature fHbp determined at 2 Å resolution is presented...

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Detalhes bibliográficos
Main Authors: Cendron, Laura, Veggi, Daniele, Girardi, Enrico, Zanotti, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087634/
https://ncbi.nlm.nih.gov/pubmed/21543855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111006154
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