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Increased Expression of Growth Differentiation Factor-15 in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension

BACKGROUND: Growth differentiation factor (GDF)-15 is a secreted member of the transforming growth factor-β cytokine superfamily. GDF-15 levels are elevated in the serum of patients with cardiovascular diseases. We hypothesized that GDF-15 levels would also be increased in the plasma and lung tissue...

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Hlavní autoři: Meadows, Christina A., Risbano, Michael G., Zhang, Li, Geraci, Mark W., Tuder, Rubin M., Collier, David H., Bull, Todd M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American College of Chest Physicians 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087455/
https://ncbi.nlm.nih.gov/pubmed/20829333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.10-0302
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