Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults

OBJECTIVE: Since Alzheimer disease (AD) neuropathology is thought to develop years before dementia, it may be possible to detect subtle AD-related atrophy in preclinical AD. Here we hypothesized that the “disease signature” of AD-related cortical thinning, previously identified in patients with mild...

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Autors principals: Dickerson, B.C., Stoub, T.R., Shah, R.C., Sperling, R.A., Killiany, R.J., Albert, M.S., Hyman, B.T., Blacker, D., deToledo-Morrell, L.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087406/
https://ncbi.nlm.nih.gov/pubmed/21490323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182166e96
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