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Determination of fetal chromosome aberrations from fetal DNA in maternal blood: has the challenge finally been met?

The analysis of cell-free fetal nucleic acids in maternal blood for prenatal diagnosis has been transformed by several recent profound technology developments. The most noteworthy of these are ‘digital PCR’ and ‘next-generation sequencing’ (NGS), which might finally deliver the long-sought goal of n...

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Detalhes bibliográficos
Main Authors: Hahn, Sinuhe, Lapaire, Olav, Tercanli, Sevgi, Kolla, Varaprasad, Hösli, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087311/
https://ncbi.nlm.nih.gov/pubmed/21542948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1462399411001852
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