OPTIMIZATION OF PEPTIDE-BASED INHIBITORS OF PROSTATE-SPECIFIC ANTIGEN (PSA) AS TARGETED IMAGING AGENTS FOR PROSTATE CANCER

Prostate-Specific Antigen (PSA) is a serine protease biomarker that may play a role in prostate cancer development and progression. The inhibition of PSA’s enzymatic activity with small molecule inhibitors is an attractive and, as of yet, unexploited target. Previously, we reported a series of pepti...

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Bibliographic Details
Main Authors: LeBeau, Aaron M., Banerjee, Sangeeta R., Pomper, Martin G., Mease, Ronnie C., Denmeade, Samuel R.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087300/
https://ncbi.nlm.nih.gov/pubmed/19541487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.06.012
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